Revealing Two Types of Bottom Designs in Cell Culture Flasks

Cell culture is a crucial process in the biomedical field, and cell culture flasks play a vital role in the initial stages of cell expansion. As a common fundamental tool, cell culture flasks are categorized based on the type of cells being cultured, featuring either a standard or baffled bottom design.

Cell culture is a crucial process in the biomedical field, and cell culture flasks play a vital role in the initial stages of cell expansion. As a common fundamental tool, cell culture flasks are categorized based on the type of cells being cultured, featuring either a standard or baffled bottom design.

Standard Bottom Cell Culture Flasks:
Standard bottom cell culture flasks are typically used in conjunction with shakers or oscillating incubators and are widely employed in the initial stages of cell expansion. These flasks feature a flat bottom surface without any additional structures or designs. This simple design is suitable for general cell culture needs, easy to operate, and has a broad range of applications.

Baffled Bottom Cell Culture Flasks:
Baffled bottom cell culture flasks incorporate a special corrugated structure in the bottom design, which increases the solubility of oxygen in the culture medium and enhances oxygen diffusion efficiency. This promotes cell metabolism and growth. Additionally, the baffled design increases the shear force within the culture medium, helping to reduce cell clumping and aggregation, thus maintaining individual cell dispersion and promoting uniform cell growth. This design is particularly suitable for the culture of suspension cells with high oxygen demands, such as lymphocytes and bone marrow cells.

The above descriptions cover the two different bottom designs of cell culture flasks, highlighting their characteristics and applications. Each design has its own advantages, meeting diverse market needs and providing essential tools for life science research.